Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745423 | 0.80 | CES1 (0.62) | ALDH1A1MAPTPOLBKMT2AAGTR1 | |
| SCHEMBL8412206 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL252198 | 0.73 | CA12 (0.68) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL7745479 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL25136853 | 0.71 | TTR (0.67) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL13114100 | 0.71 | TTR (0.67) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL6317943 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBKMT2AAGTR1 | |
| SCHEMBL6317939 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBKMT2AAGTR1 | |
| SCHEMBL7564529 | 0.69 | CA12 (0.56) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL7564533 | 0.69 | CA12 (0.56) | ALDH1A1MAPTPOLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |