Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740953 | 0.91 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBLMNAKDM4E | |
| SCHEMBL7745310 | 0.86 | POLB (0.45) | ALDH1A1MAPTPOLBLMNAKDM4E | |
| SCHEMBL7746032 | 0.77 | FFAR4 (0.39) | MAPTLMNAKMT2A | |
| SCHEMBL7745904 | 0.74 | DRD2 (0.44) | ALDH1A1MAPTPOLBLMNAKDM4E | |
| SCHEMBL7740752 | 0.74 | DRD2 (0.44) | ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL7741406 | 0.74 | DRD2 (0.44) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL7740267 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBLMNAKDM4E | |
| SCHEMBL281270 | 0.72 | CES1 (0.63) | ALDH1A1MAPTTP53 | |
| SCHEMBL14597968 | 0.70 | HDAC1 (0.67) | POLBKMT2AHPGDTP53PTPN1 | |
| SCHEMBL7745438 | 0.68 | MEN1 (0.60) | ALDH1A1MAPTPOLBKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |