Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740434 | 0.74 | PGK1 (0.40) | PGK1LMNAMAPTMEN1NPC1 | |
| SCHEMBL1387903 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2HTTALDH1A1TMIGD3ADORA2A | |
| SCHEMBL7739866 | 0.67 | KDM4E (0.34) | KDM4E | |
| SCHEMBL7740436 | 0.67 | ENPP1 (0.37) | ENPP1PGK1HTR2BSMN1; SMN2HTT | |
| SCHEMBL1388236 | 0.60 | PDE4A (0.52) | SMN1; SMN2HTTALDH1A1ADORA2A | |
| SCHEMBL7998657 | 0.60 | CDK1 (0.59) | LMNAMAPTMEN1NR2F2RAB9A | |
| Hydrochloric Acid SCHEMBL7326513 | 0.59 | PDE4A (0.51) | SMN1; SMN2HTTALDH1A1ADORA2A | |
| SCHEMBL1388188 | 0.57 | ADORA2A (0.39) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8978330 | 0.56 | YTHDC1 (0.41) | KMT2ASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL1388038 | 0.56 | ADORA2A (0.41) | LMNAKMT2AKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413975-B1 | DISEASES WITH HIGH LEVELS OF INFLAMMATORY CYTOKINES; ASTHMA; ALLERGIES; INFLAMMATION; DEPRESSION; ALZHEIMER'S DISEASE; VASCULAR AND MULTI-IN-FARCT DEMENTIA | EURO-CELTIQUE, S.A. (LU) | 2002-07-02 | — | — | US | disclosed |
| US-6319928-B1 | ASTHMA, ALLERGIES, INFLAMMATION,DEPRESSION, DEMENTIA, ALZHEIMER'S DISEASE, VASCULAR AND MULTI-IN-FARCT DEMENTIA AND DISEASE CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS TREATMENT; EFFICIENCY AND SELECTIVITY | EURO-CELTIQUE, S.A. (LU) | 2001-11-20 | — | — | US | disclosed |
| US-6294541-B1 | ENZYME INHIBITORS USING PURINE COMPOUNDS AS ANTIHISTAMINES | EURO-CELTIQUE S.A. (LU) | 2001-09-25 | — | — | US | disclosed |