Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793308 | 1.00 | IDO1 (0.53) | IDO1ALDH1A1HTTHPGDUSP2 | |
| SCHEMBL5951828 | 0.89 | MEN1 (0.56) | IDO1ALDH1A1HTTHPGDUSP2 | |
| SCHEMBL29861059 | 0.87 | ALDH1A1 (0.64) | IDO1ALDH1A1HTTHPGDUSP2 | |
| SCHEMBL7793336 | 0.87 | ALDH1A1 (0.64) | IDO1ALDH1A1HTTHPGDUSP2 | |
| SCHEMBL1460061 | 0.85 | KDM4E (0.58) | ALDH1A1HTTHPGDMEN1KMT2A | |
| SCHEMBL14770690 | 0.85 | MLKL (0.52) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL13373953 | 0.85 | MEN1 (0.46) | ALDH1A1HTTHPGDMEN1KMT2A | |
| SCHEMBL5096626 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDMEN1KMT2A | |
| SCHEMBL14770549 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HTTHPGDMEN1KMT2A | |
| SCHEMBL9867044 | 0.78 | ALDH1A1 (0.75) | IDO1ALDH1A1HTTHPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |