Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | USP2 | O75604 | 2/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867054 | 0.86 | ALDH1A1 (1.00) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL2757079 | 0.84 | KDM4E (0.59) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL25160354 | 0.81 | CYP1A2 (0.54) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL18259723 | 0.81 | MLKL (0.69) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL4573758 | 0.81 | CYP1A2 (0.53) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL11317553 | 0.79 | CYP1A2 (0.51) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL17179726 | 0.79 | ALPL (0.75) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL12727236 | 0.78 | CYP1A2 (0.50) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL7793308 | 0.78 | IDO1 (0.53) | ALDH1A1USP2HPGDHTTCYP1A2 | |
| SCHEMBL7740448 | 0.78 | IDO1 (0.53) | ALDH1A1USP2HPGDHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015473-A | Beta-lactamase inhibitors | PFIZER INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4826833-A | ANTIBIOTICS | PFIZER INC. (US) | 1989-05-02 | — | — | US | disclosed |