Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861059 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HPGDHTTUSP2ALPL | |
| SCHEMBL7740448 | 0.87 | IDO1 (0.53) | ALDH1A1HPGDHTTUSP2ALPL | |
| SCHEMBL7793308 | 0.87 | IDO1 (0.53) | ALDH1A1HPGDHTTUSP2ALPL | |
| SCHEMBL6978538 | 0.85 | KDM4E (0.58) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL7508541 | 0.79 | GRIN1 (0.57) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL9867054 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDHTTUSP2ALPL | |
| SCHEMBL5951828 | 0.76 | MEN1 (0.56) | ALDH1A1HPGDHTTUSP2MEN1 | |
| SCHEMBL29439014 | 0.76 | KDM4E (0.61) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL4371528 | 0.76 | KDM4E (0.61) | ALDH1A1HPGDHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8565840 | 0.76 | AAK1 (0.63) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039291-A1 | Compositions and methods of treatment for cancer or viral infections | THE PROCTER & GAMBLE COMPANY | 2001-11-08 | — | — | US | disclosed |
| US-6110953-A | Pharmaceutical composition for inhibiting the growth of cancers | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0954309-A1 | HIV AND CANCER TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998051303-A1 | HIV AND CANCER TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-19 | — | — | WO | disclosed |
| EP-0841920-A2 | USE OF 1H-1,2,4-TRIAZOLE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0841914-A2 | USE OF GRISEOFULVIN FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005870-A2 | USE OF GRISEOFULVIN FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-20 | — | — | WO | disclosed |
| WO-1997005872-A2 | USE OF 1H-1,2,4-TRIAZOLE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039291-A1 | Compositions and methods of treatment for cancer or viral infections | TP53, HAVCR2, MAVS | ALDH1A1 1764/4885HPGD 2672/4885HTT 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.