Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118101 | 0.86 | NR1H2 (0.56) | NR1H2NR1H3LTA4HPRSS1PRSS2 | |
| SCHEMBL8836682 | 0.74 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL3241768 | 0.73 | NPC1 (0.47) | CYSLTR1CYP4F2CYP4A11PTPRCPTPN2 | |
| SCHEMBL7739084 | 0.73 | NR1H2 (0.53) | NR1H2NR1H3CYP4F2CYP4A11 | |
| SCHEMBL2455996 | 0.73 | NR1H2 (0.51) | NR1H2NR1H3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10522173 | 0.72 | NR1H2 (0.59) | NR1H2NR1H3CYSLTR1NPC1RAB9A | |
| SCHEMBL8991100 | 0.71 | MAOB (0.64) | APPNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL18637175 | 0.71 | RXRA (0.64) | APPNPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL5512106 | 0.71 | APP (0.67) | APPNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL4054115 | 0.71 | MAOB (0.64) | APPNPC1CASP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |