Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740893 | 0.88 | L3MBTL1 (0.48) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL97962 | 0.78 | CA2 (0.48) | CA2CA1NAMPTPOLB | |
| SCHEMBL694269 | 0.76 | CA2 (0.54) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL100146 | 0.76 | KDM4E (0.60) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL12283041 | 0.76 | NPC1 (0.60) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL1569661 | 0.76 | CA2 (0.56) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL27741035 | 0.76 | CA2 (0.56) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL21314041 | 0.76 | CA1 (0.52) | CA2CA1NAMPTALDH1A1 | |
| SCHEMBL8757517 | 0.75 | CA2 (0.53) | CA2CA1NAMPTMAPTTDP1 | |
| SCHEMBL693427 | 0.75 | CA2 (0.53) | CA2CA1NAMPTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |