Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740860 | 0.88 | CA2 (0.47) | NAMPTNR1H2NR1H3GAACA1 | |
| SCHEMBL7739224 | 0.81 | NR1H2 (0.40) | L3MBTL1NR1H2NR1H3GAACA1 | |
| SCHEMBL3180689 | 0.80 | L3MBTL1 (0.61) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL7740834 | 0.79 | ACE (0.53) | — | |
| SCHEMBL13977501 | 0.79 | NAMPT (0.52) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL19853209 | 0.78 | L3MBTL1 (0.51) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL6021904 | 0.77 | L3MBTL1 (0.53) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL3307112 | 0.76 | L3MBTL1 (0.52) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL1580051 | 0.76 | L3MBTL1 (0.54) | L3MBTL1NAMPTGAACA1CA2 | |
| SCHEMBL7739226 | 0.76 | CTSS (0.45) | NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |