Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741469 | 0.91 | PTGDR2 (0.42) | CHRM5CA1CA2CA12CA9 | |
| SCHEMBL7745598 | 0.85 | PTPN7 (0.37) | CHRM5CA1CA2CA9UCHL1 | |
| SCHEMBL13627976 | 0.77 | CA1 (0.52) | CHRM5CA1CA2CA12CA9 | |
| SCHEMBL7746032 | 0.76 | FFAR4 (0.39) | PARK7CASP3MEN1NPC1LMNA | |
| SCHEMBL7746063 | 0.73 | IDO1 (0.35) | CHRM5CA1CA2CA12CA9 | |
| SCHEMBL7741233 | 0.73 | TBXA2R (0.34) | CHRM5CA1CA2CA12CA9 | |
| SCHEMBL7745380 | 0.71 | TBXA2R (0.39) | CA1CA2CA12CA9 | |
| SCHEMBL7745479 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL13627970 | 0.65 | CHRM5 (0.53) | CHRM5CA1CA2CA12CA9 | |
| SCHEMBL13627937 | 0.64 | CHRM5 (0.55) | CHRM5CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |