Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741102 | 0.91 | CHRM5 (0.39) | PTGDR2PARK7MAPTCA1CA2 | |
| SCHEMBL7746032 | 0.85 | FFAR4 (0.39) | PARK7MAPTMAPK1TRPA1MEN1 | |
| SCHEMBL7745598 | 0.76 | PTPN7 (0.37) | MAPK1CA1CA2CA9CHRM5 | |
| SCHEMBL13627976 | 0.75 | CA1 (0.52) | PARK7CA1CA2CA12CA9 | |
| SCHEMBL7746063 | 0.74 | IDO1 (0.35) | CA1CA2CA12CA9TBXA2R | |
| SCHEMBL7741233 | 0.73 | TBXA2R (0.34) | CA1CA2CA12CA9TBXA2R | |
| SCHEMBL7745380 | 0.71 | TBXA2R (0.39) | CA1CA2CA12CA9TBXA2R | |
| SCHEMBL14884742 | 0.71 | PARK7 (0.65) | PARK7CA1CA2CA12CA9 | |
| SCHEMBL7740953 | 0.70 | ALDH1A1 (0.45) | MAPTNPSR1MEN1POLBKMT2A | |
| SCHEMBL6317571 | 0.65 | ALDH1A1 (0.49) | MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |