Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740953 | 0.86 | ALDH1A1 (0.45) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL7741469 | 0.85 | PTGDR2 (0.42) | MEN1MAPK1KMT2AMAPTTRPA1 | |
| SCHEMBL7741250 | 0.76 | AGTR1 (0.36) | PTPN7LMNAMAPT | |
| SCHEMBL7741102 | 0.76 | CHRM5 (0.39) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL7745715 | 0.75 | AGTR1 (0.35) | — | |
| SCHEMBL7745310 | 0.74 | POLB (0.45) | KMT2ALMNAMAPT | |
| SCHEMBL7746494 | 0.73 | MAPT (0.39) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL7741615 | 0.73 | CNR2 (0.42) | — | |
| SCHEMBL14884742 | 0.69 | PARK7 (0.65) | TRPA1PARK7 | |
| SCHEMBL13627970 | 0.66 | CHRM5 (0.53) | CASP3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |