Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23466822 | 0.86 | FDPS (0.38) | CYP4F2CYP4A11CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11328716 | 0.82 | L3MBTL1 (0.39) | CYP2D6CYP2C9CYP2C19KMT2AALDH1A1 | |
| SCHEMBL7710917 | 0.80 | MMP8 (0.38) | CYP4F2CYP4A11CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2357224 | 0.80 | MMP8 (0.38) | CYP4F2CYP4A11CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11595497 | 0.79 | CYP2D6 (0.38) | CYP4F2CYP4A11CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL246602 | 0.77 | LAP3 (0.37) | MMP8MEN1KMT2ALAP3FDPS | |
| SCHEMBL17617109 | 0.73 | MMP8 (0.41) | CYP4F2CYP4A11MMP8PKMKDM4E | |
| SCHEMBL17617114 | 0.72 | MMP8 (0.43) | CYP4F2CYP4A11MMP8PKMKDM4E | |
| Ammonia Solution, Strong SCHEMBL28085900 | 0.72 | MMP8 (0.40) | CYP4F2CYP4A11MMP8PKMKDM4E | |
| SCHEMBL13269674 | 0.70 | CYP4F2 (0.37) | CYP4F2CYP4A11MMP8PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |