Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054626 | 0.83 | KDM4E (0.43) | ALDH1A1NPSR1KDM4EGAAHTT | |
| SCHEMBL8380078 | 0.74 | MAPT (0.51) | GLAALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL9860824 | 0.73 | MAPT (0.50) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL10338495 | 0.73 | MAPT (0.50) | ALDH1A1HPGDMAPTKDM4EGAA | |
| Acetic Acid SCHEMBL25297545 | 0.70 | NCEH1 (0.48) | GLAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL9052921 | 0.70 | CYP2C9 (0.55) | CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL7067944 | 0.70 | TUBB4A (0.46) | ALDH1A1NPSR1GAACYP3A4CYP2C9 | |
| SCHEMBL23499940 | 0.70 | MEN1 (0.63) | GLAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL5916381 | 0.70 | LMNA (0.44) | ALDH1A1HPGDKDM4ECYP2C9MEN1 | |
| SCHEMBL4834321 | 0.70 | ALDH1A1 (0.52) | GLAALDH1A1HPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |