Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741242 | 0.83 | GLA (0.44) | KDM4EALDH1A1KMT2AHTTNPSR1 | |
| SCHEMBL7067944 | 0.74 | TUBB4A (0.46) | ALDH1A1TSHRNPSR1GAAACHE | |
| SCHEMBL9052739 | 0.74 | BCHE (0.45) | ALDH1A1TSHRL3MBTL1LMNATAS1R3 | |
| SCHEMBL5916381 | 0.74 | LMNA (0.44) | KDM4EPOLBALDH1A1TSHRKMT2A | |
| SCHEMBL27665536 | 0.70 | CA1 (0.39) | KDM4ECA1CA2CA12CA7 | |
| Propionic Acid SCHEMBL27946489 | 0.69 | KDM4E (0.56) | KDM4ECA1CA2CA12CA7 | |
| SCHEMBL18686368 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TSHRKMT2AHTT | |
| SCHEMBL3096724 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1KMT2AHTTNPSR1 | |
| SCHEMBL8007725 | 0.69 | CPN1 (0.47) | KDM4EPOLBSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10750670 | 0.68 | HTT (0.40) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |