Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741627 | 0.94 | CNR2 (0.38) | AGTR1AGTR2IDO1DRD2TBXA2R | |
| SCHEMBL7745710 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2GLP1RTP53POLB | |
| SCHEMBL7741615 | 0.90 | CNR2 (0.42) | TBXA2RIDH1CNR2 | |
| SCHEMBL7746063 | 0.87 | IDO1 (0.35) | IDO1TBXA2RCNR2 | |
| SCHEMBL7745904 | 0.85 | DRD2 (0.44) | TP53POLBDRD2TBXA2RLMNA | |
| SCHEMBL7745715 | 0.82 | AGTR1 (0.35) | AGTR1AGTR2DRD2TBXA2RIDH1 | |
| SCHEMBL7746494 | 0.82 | MAPT (0.39) | TP53DRD2TBXA2RLMNAMAPT | |
| SCHEMBL7741465 | 0.81 | AGTR1 (0.36) | AGTR1AGTR2TP53POLBDRD2 | |
| SCHEMBL7741233 | 0.78 | TBXA2R (0.34) | AGTR1AGTR2TBXA2R | |
| SCHEMBL7745883 | 0.78 | AGTR1 (0.42) | AGTR1AGTR2GLP1RPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |