Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741465 | 0.95 | AGTR1 (0.36) | MAPTLMNADRD2TBXA2RTP53 | |
| SCHEMBL7745385 | 0.87 | AGTR1 (0.42) | TBXA2R | |
| SCHEMBL7746035 | 0.86 | AGTR1 (0.36) | TBXA2R | |
| SCHEMBL7745380 | 0.83 | TBXA2R (0.39) | TBXA2R | |
| SCHEMBL7741250 | 0.82 | AGTR1 (0.36) | MAPTLMNADRD2TBXA2RTP53 | |
| SCHEMBL7741627 | 0.82 | CNR2 (0.38) | DRD2TBXA2R | |
| SCHEMBL7745710 | 0.82 | AGTR1 (0.38) | DRD2TBXA2RTP53 | |
| SCHEMBL7745715 | 0.80 | AGTR1 (0.35) | DRD2TBXA2R | |
| SCHEMBL7740752 | 0.79 | DRD2 (0.44) | MAPTLMNADRD2TBXA2RPTGDR2 | |
| SCHEMBL7741406 | 0.79 | DRD2 (0.44) | MAPTLMNADRD2TBXA2RPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |