Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 3/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741295 | 0.98 | TXNRD1 (0.52) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA | |
| SCHEMBL20493758 | 0.97 | TXNRD1 (0.50) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA | |
| SCHEMBL27152743 | 0.92 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA | |
| SCHEMBL10978656 | 0.77 | CDK2 (0.37) | TXNRD1TXNRD3TXNRD2CYP1A2CYP1A1 | |
| SCHEMBL8370836 | 0.77 | ALDH1A1 (0.41) | CYP1A2AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL10979960 | 0.77 | CES1 (0.39) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA | |
| SCHEMBL7742191 | 0.77 | CES1 (0.39) | CYP1A2AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL11113521 | 0.77 | CES1 (0.36) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA | |
| SCHEMBL7741289 | 0.76 | CES1 (0.38) | CYP1A2AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL1042592 | 0.75 | MAPT (0.63) | TXNRD1TXNRD3TXNRD2CYP1A2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6428912-B1 | ALUMINUM TRIS(9-OXIDOPHENALENONE) OR TRIS(6-OXIDOBENZANTHRONE) DERIVATIVE CHELATE COMPOUNDS; ELECTROLUMINESCENT | AGERE SYSTEMS GUARDIAN CORP. | 2002-08-06 | — | — | US | claimed |
| US-6428912-B1 | ALUMINUM TRIS(9-OXIDOPHENALENONE) OR TRIS(6-OXIDOBENZANTHRONE) DERIVATIVE CHELATE COMPOUNDS; ELECTROLUMINESCENT | AGERE SYSTEMS GUARDIAN CORP. | 2002-08-06 | — | — | US | disclosed |
| US-6428912-B1 | ALUMINUM TRIS(9-OXIDOPHENALENONE) OR TRIS(6-OXIDOBENZANTHRONE) DERIVATIVE CHELATE COMPOUNDS; ELECTROLUMINESCENT | AGERE SYSTEMS GUARDIAN CORP. | 2002-08-06 | — | — | US | disclosed |