SCHEMBL10978656

SCHEMBL10978656

Oc1ccc2cccc3c2c1C(=S)C=C3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.37
ALDH1A1 P00352 3/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
DNMT1 P26358 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
MCL1 Q07820 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10978229 0.79 ALDH1A1 (0.34) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10980405 0.79 ALDH1A1 (0.34) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL7741295 0.79 TXNRD1 (0.52) CDK2ALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL20493758 0.77 TXNRD1 (0.50) CDK2ALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL7741285 0.77 TXNRD1 (0.50) CDK2ALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL27152743 0.73 TXNRD1 (0.46) CDK2ALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL119916 0.73 CDK2 (0.41) CDK2ALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL1081981 0.71 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL28278114 0.70 ALDH1A1 (0.35) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL28820242 0.69 ALDH1A1 (0.41) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069292-B1 POLYMERS WITH AT LEAST TWO STABLE AND REVERSIBLY INTERCHANGEABLE OXIDATION STEPS, PROCESS FOR THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1985-05-15 EP disclosed