SCHEMBL7741295

SCHEMBL7741295

O=C1C=Cc2cccc3ccc(O)c1c23

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 3/20 0.52
TXNRD3 Q86VQ6 3/20 0.52
TXNRD2 Q9NNW7 3/20 0.52
CYP1A2 P05177 3/20 0.52
AURKA O14965 2/20 0.52
CDC25B P30305 2/20 0.52
AURKB Q96GD4 2/20 0.52
CYP1A1 P04798 2/20 0.52
COPS5 Q92905 1/20 0.52
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
ALDH1A1 P00352 6/20 0.47
HPGD P15428 6/20 0.47
HSD17B10 Q99714 5/20 0.47
MAPT P10636 5/20 0.47
MAPK1 P28482 4/20 0.47
ALOX15 P16050 4/20 0.47
CYP3A4 P08684 3/20 0.47
TP53 P04637 3/20 0.47
KDM4E B2RXH2 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741285 0.98 TXNRD1 (0.50) TXNRD1TXNRD3TXNRD2CYP1A2AURKA
SCHEMBL20493758 0.98 TXNRD1 (0.50) TXNRD1TXNRD3TXNRD2CYP1A2AURKA
SCHEMBL27152743 0.94 TXNRD1 (0.46) TXNRD1TXNRD3TXNRD2CYP1A2AURKA
SCHEMBL10978656 0.79 CDK2 (0.37) TXNRD1TXNRD3TXNRD2CYP1A2CYP1A1
SCHEMBL8370836 0.79 ALDH1A1 (0.41) CYP1A2AURKACDC25BAURKBCYP1A1
SCHEMBL10979960 0.79 CES1 (0.39) TXNRD1TXNRD3TXNRD2CYP1A2AURKA
SCHEMBL7742191 0.79 CES1 (0.39) CYP1A2AURKACDC25BAURKBCYP1A1
SCHEMBL11113521 0.78 CES1 (0.36) TXNRD1TXNRD3TXNRD2CYP1A2AURKA
SCHEMBL7741289 0.77 CES1 (0.38) CYP1A2AURKACDC25BAURKBCYP1A1
SCHEMBL1042592 0.77 MAPT (0.63) TXNRD1TXNRD3TXNRD2CYP1A2AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
US-20240210368-A1 SENSOR ELEMENT FOR AN OPTOCHEMICAL SENSOR ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) 2024-06-27 US claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
US-20170097530-A1 PHOTO-CONVERSION MEANS FOR LIQUID CRYSTAL DISPLAYS AU OPTRONICS CORPORATION (TW) 2017-04-06 US claimed
WO-1992010555-A1 FLUORESCENT COMPOUNDS FOR ABSORPTION AND RE-EMISSION OF RADIATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO claimed
US-5095099-A Fluorescent compounds for absorption and re-emission of radiation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-10 US claimed
US-12504547-B2 Sensor and sensor device for determining a radiation dose, read-out device for reading out a sensor, and method for determining a radiation dose PRUUVE GMBH (DE) 2025-12-23 US disclosed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US disclosed
US-20240210368-A1 SENSOR ELEMENT FOR AN OPTOCHEMICAL SENSOR ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) 2024-06-27 US disclosed
CN-118225741-A Sensor element for a photochemical sensor 恩德莱斯和豪瑟尔分析仪表两合公司 2024-06-21 CN disclosed
EP-4327132-A1 SENSOR AND SENSOR DEVICE FOR DETERMINING A RADIATION DOSE, READ-OUT DEVICE FOR READING OUT A SENSOR, AND METHOD FOR DETERMINING A RADIATION DOSE Technische Universität Dresden (DE) 2024-02-28 EP disclosed
US-20240045082-A1 SENSOR AND SENSOR DEVICE FOR DETERMINING A RADIATION DOSE, READ-OUT DEVICE FOR READING OUT A SENSOR, AND METHOD FOR DETERMINING A RADIATION DOSE PRUUVE GMBH (DE) 2024-02-08 US disclosed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US disclosed
US-4518535-A Preparation of electrically conductive systems from substituted phenalenes, and the products obtained BASF AKTIENGESELLSCHAFT (DE) 1985-05-21 US disclosed
EP-0069292-B1 POLYMERS WITH AT LEAST TWO STABLE AND REVERSIBLY INTERCHANGEABLE OXIDATION STEPS, PROCESS FOR THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1985-05-15 EP disclosed
US-4468509-A FROM ACETYLENE DERIVATIVES OF 1,9--DISUBSTITUTED PHENALENE BASF AKTIENGESELLSCHAFT (DE) 1984-08-28 US disclosed
US-4464511-A ELECTROCONDUCTIVITY, ELECTROCHROMIC, ANTISTATIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 1984-08-07 US disclosed
EP-0104388-A2 Reversible oxidizable or reducible polymers with polyene units, process for their preparation and their use BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed
EP-0093967-A2 Process for the preparation of electrically conductive systems from substituted phenalenes, products so prepared and their application BASF Aktiengesellschaft (DE) 1983-11-16 EP disclosed
EP-0069292-A1 Polymers with at least two stable and reversibly interchangeable oxidation steps, process for their preparation and their use BASF Aktiengesellschaft (DE) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof AGL, GMNN, GAK TXNRD1 3586/4885TXNRD3 4250/4885TXNRD2 3887/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK TXNRD1 3586/4885TXNRD3 4250/4885TXNRD2 3887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.