SCHEMBL7741644

SCHEMBL7741644

CC(C)(C)Oc1ccc([I+](OS(=O)(=O)c2ccc(C(c3ccccc3)c3ccccc3)cc2)c2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
MMP13 P45452 1/20 0.31
ABCB1 P08183 1/20 0.31
ACACB O00763 1/20 0.30
AKR1C3 P42330 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64192 0.86 HTT (0.42) MEN1KMT2ACA12CA1CA2
SCHEMBL7739970 0.86 MMP13 (0.43) CYP19A1ALDH1A1MAPTHTTMMP13
SCHEMBL7739940 0.85 CA12 (0.35) MEN1KMT2ACA12CA1CA2
SCHEMBL7739948 0.84 HSD11B1 (0.43) MEN1KMT2ACA1CA2ALDH1A1
SCHEMBL7738083 0.83 ALDH1A1 (0.39) CYP19A1CA12CA1CA2CA7
SCHEMBL7733589 0.79 MEN1 (0.36) CYP19A1MEN1KMT2ACA12CA1
SCHEMBL13098196 0.77 SLC6A2 (0.40) ALDH1A1ACACB
SCHEMBL13098213 0.77 SLC6A2 (0.40) ALDH1A1ACACB
SCHEMBL64775 0.75 PPARA (0.32) MEN1KMT2APPARA
SCHEMBL5707386 0.75 LMNA (0.34) ALDH1A1HTTABCB1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed