SCHEMBL7741645

SCHEMBL7741645

CC(C)(C)Oc1ccc(-c2ccccc2I)cc1.O=S(=O)(O)c1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.36
PPARA Q07869 3/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PPARD Q03181 1/20 0.36
PTGS2 P35354 4/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ADAMTS4 O75173 2/20 0.32
GRIA4 P48058 1/20 0.32
DAGLA Q9Y4D2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7739971 0.87 PDE4A (0.42) PTGS2TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL1140939 0.86 ALDH1A1 (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL218886 0.86 ALDH1A1 (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL7738086 0.84 CA12 (0.39) PPARGPPARACYP2C9CYP2C19PPARD
Sulfuric Acid SCHEMBL15345263 0.81 PPARG (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL5707388 0.80 PPARA (0.41) PPARGPPARACYP2C9CYP2C19PPARD
Trifluoromethanesulfonic Acid SCHEMBL1140970 0.78 PPARG (0.39) PPARGPPARACYP2C9CYP2C19PPARD
Trifluoromethanesulfonic Acid SCHEMBL216502 0.78 PPARG (0.39) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL248258 0.78 PPARG (0.41) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL4655793 0.76 HDAC4 (0.47) PTGS2TSHRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed