Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718070 | 0.77 | KDM4E (0.53) | MTNR1AMTNR1BHSD17B10KDM4E | |
| SCHEMBL6633664 | 0.73 | MTNR1A (0.62) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| SCHEMBL11598281 | 0.71 | MTNR1A (0.52) | MTNR1AMTNR1BHSD17B10KDM4E | |
| SCHEMBL7741714 | 0.68 | MTNR1A (0.47) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| SCHEMBL7459894 | 0.68 | KDM4E (0.53) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| Propionic Acid SCHEMBL7100623 | 0.68 | CYP1A2 (0.68) | HSD17B10PTGS1AKR1C3AKR1C2KDM4E | |
| SCHEMBL10388487 | 0.67 | KDM4E (0.56) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| SCHEMBL6637953 | 0.67 | MTNR1A (0.60) | MTNR1AMTNR1BHSD17B10KDM4E | |
| SCHEMBL7456021 | 0.66 | KDM4E (0.58) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| SCHEMBL30692247 | 0.65 | MTNR1A (0.64) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |