Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637953 | 0.77 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8600249 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL7741712 | 0.74 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8669796 | 0.74 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL11893016 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL7016797 | 0.73 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL8406900 | 0.72 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL27002090 | 0.72 | HSD17B10 (0.59) | PPARDPPARA | |
| SCHEMBL8673938 | 0.72 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL15292203 | 0.72 | MTNR1A (0.56) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |