Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 10/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743442 | 0.78 | HTR1A (0.44) | — | |
| SCHEMBL7735711 | 0.74 | MTNR1B (0.43) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL27521768 | 0.73 | PDPK1 (0.36) | MTNR1A | |
| SCHEMBL7735727 | 0.72 | MTNR1A (0.65) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL6633828 | 0.72 | MTNR1A (0.58) | MTNR1BMTNR1A | |
| SCHEMBL6254036 | 0.70 | MTNR1B (0.58) | MTNR1BMTNR1A | |
| SCHEMBL6632981 | 0.66 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL7740264 | 0.64 | MTNR1B (0.69) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL6257306 | 0.64 | MTNR1B (0.54) | MTNR1BMTNR1A | |
| SCHEMBL6632974 | 0.64 | MTNR1B (1.00) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |