Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 17/20 | 0.69 |
| ▸ | MTNR1A | P48039 | 16/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | NQO2 | P16083 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632759 | 0.82 | MTNR1B (1.00) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL6634273 | 0.81 | MTNR1B (0.81) | MTNR1BMTNR1A | |
| SCHEMBL4688742 | 0.79 | MTNR1B (0.76) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL7740272 | 0.79 | HTR1A (0.66) | MTNR1BMTNR1AHTR1ANQO2 | |
| SCHEMBL4685587 | 0.79 | MTNR1B (0.66) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL7741709 | 0.78 | HTR1A (0.81) | MTNR1BMTNR1AHTR1ANQO2 | |
| SCHEMBL7743293 | 0.77 | HTR1A (1.00) | MTNR1BMTNR1AHTR1A | |
| SCHEMBL7741718 | 0.77 | HTR1A (0.57) | MTNR1BMTNR1AHTR1ANQO2 | |
| SCHEMBL7740269 | 0.76 | MTNR1B (0.61) | MTNR1BMTNR1AHTR1ANQO2 | |
| SCHEMBL7735741 | 0.73 | MTNR1A (0.51) | MTNR1BMTNR1AHTR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |