Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CD40 | P25942 | 1/20 | 0.41 |
| ▸ | CD40LG | P29965 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621243 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MYCMAX | |
| SCHEMBL7611513 | 0.81 | SLC6A3 (0.42) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL9754422 | 0.77 | CA1 (0.48) | ALDH1A1MYCMAXPOLBMAPK1 | |
| SCHEMBL17796945 | 0.77 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1MYCMAX | |
| SCHEMBL17289272 | 0.77 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1MYCMAX | |
| SCHEMBL7616828 | 0.77 | IKBKB (0.52) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL16879409 | 0.74 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1MYCMAX | |
| Phenylurea SCHEMBL27473020 | 0.74 | MEN1 (0.63) | MEN1KMT2AALDH1A1POLBMAPK1 | |
| SCHEMBL11612279 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MYCMAX | |
| SCHEMBL7615106 | 0.73 | KIF11 (0.63) | ALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417393-B1 | TREATMENT OF SICKLE-CELL ANEMIA, BRAIN EDEMA FROM TUMORS OR ISCHEMIA, DIARRHEA, AND GLAUCOMA; HYPOTENSIVE, WOUND HEALING, ANTIINFLAMMATORY AND ANTIALLERGEN AGENTS | NEUROSEARCH A/S (DK) | 2002-07-09 | — | — | US | disclosed |
| EP-0906273-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045400-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |