Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745965 | 0.90 | SMN1; SMN2 (0.58) | FAAHPTGDR2RECQLTP53KDM4E | |
| SCHEMBL22965212 | 0.84 | PTGDR2 (0.59) | FAAHPTGDR2TP53KDM4EHSD17B10 | |
| SCHEMBL22965246 | 0.84 | PTGDR2 (0.54) | FAAHPTGDR2RECQLKDM4EHSD17B10 | |
| SCHEMBL22965231 | 0.83 | TSHR (0.59) | FAAHPTGDR2RECQLKDM4EHSD17B10 | |
| SCHEMBL30536652 | 0.81 | KDM4E (0.53) | FAAHPTGDR2RECQLKDM4EHSD17B10 | |
| SCHEMBL7746512 | 0.81 | PTGDR2 (0.48) | FAAHPTGDR2RECQLKDM4EHSD17B10 | |
| SCHEMBL16421862 | 0.81 | GAA (0.59) | FAAHPTGDR2TP53KDM4EHSD17B10 | |
| SCHEMBL3003332 | 0.81 | PTGDR2 (0.55) | FAAHPTGDR2TP53KDM4EHSD17B10 | |
| SCHEMBL9430801 | 0.81 | PTGDR2 (0.55) | FAAHPTGDR2KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL30184968 | 0.80 | TLR8 (0.65) | RECQLTP53SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |