Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965246 | 0.87 | PTGDR2 (0.54) | L3MBTL1PTGDR2KDM4EHSD17B10TNF | |
| SCHEMBL25400141 | 0.84 | KDM4E (0.53) | PTGDR2KDM4EHSD17B10TNFHPGD | |
| SCHEMBL30536652 | 0.84 | KDM4E (0.53) | PTGDR2KDM4EHSD17B10TNFHPGD | |
| SCHEMBL16421862 | 0.84 | GAA (0.59) | PTGDR2LMNAKDM4EHSD17B10TNF | |
| SCHEMBL7745965 | 0.84 | SMN1; SMN2 (0.58) | PTGDR2LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL7741979 | 0.83 | FAAH (0.56) | PTGDR2LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL22965154 | 0.81 | KDM4E (0.62) | PTGDR2KDM4EHSD17B10TNFHPGD | |
| SCHEMBL22965212 | 0.81 | PTGDR2 (0.59) | PTGDR2LMNAKDM4EHSD17B10TNF | |
| SCHEMBL22965259 | 0.80 | PTGDR2 (0.63) | L3MBTL1PTGDR2LMNAKDM4EHSD17B10 | |
| SCHEMBL22965222 | 0.79 | ALDH1A1 (0.54) | TSHRPTGDR2LMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |