Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741979 | 0.90 | FAAH (0.56) | SMN1; SMN2FAAHKDM4ELMNAPTGDR2 | |
| SCHEMBL22965212 | 0.85 | PTGDR2 (0.59) | FAAHKDM4ELMNAPTGDR2TP53 | |
| SCHEMBL22965246 | 0.85 | PTGDR2 (0.54) | SMN1; SMN2FAAHKDM4EPTGDR2RECQL | |
| SCHEMBL22965231 | 0.84 | TSHR (0.59) | SMN1; SMN2FAAHKDM4ELMNAPTGDR2 | |
| SCHEMBL30536652 | 0.82 | KDM4E (0.53) | SMN1; SMN2FAAHKMT2AKDM4EPTGDR2 | |
| SCHEMBL7746512 | 0.82 | PTGDR2 (0.48) | SMN1; SMN2FAAHKDM4EPTGDR2RECQL | |
| SCHEMBL16421862 | 0.82 | GAA (0.59) | FAAHKDM4ELMNAPTGDR2TP53 | |
| SCHEMBL9430801 | 0.81 | PTGDR2 (0.55) | SMN1; SMN2FAAHKDM4ELMNAPTGDR2 | |
| SCHEMBL3003332 | 0.81 | PTGDR2 (0.55) | SMN1; SMN2FAAHKMT2AKDM4EPTGDR2 | |
| SCHEMBL8268110 | 0.81 | FAAH (0.54) | SMN1; SMN2FAAHKDM4ELMNAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |