Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965212 | 0.85 | PTGDR2 (0.59) | PTGDR2FAAHKDM4EHSD17B10LMNA | |
| SCHEMBL16421862 | 0.82 | GAA (0.59) | PTGDR2FAAHKDM4EHSD17B10LMNA | |
| SCHEMBL3003332 | 0.81 | PTGDR2 (0.55) | PTGDR2SMN1; SMN2FAAHKDM4EHSD17B10 | |
| SCHEMBL7745965 | 0.81 | SMN1; SMN2 (0.58) | PTGDR2SMN1; SMN2FAAHKDM4EHSD17B10 | |
| SCHEMBL7741979 | 0.81 | FAAH (0.56) | PTGDR2SMN1; SMN2FAAHKDM4EHSD17B10 | |
| SCHEMBL8268109 | 0.80 | PTGDR2 (0.53) | PTGDR2SMN1; SMN2FAAHKDM4EHSD17B10 | |
| SCHEMBL8268110 | 0.79 | FAAH (0.54) | PTGDR2SMN1; SMN2FAAHKDM4EHSD17B10 | |
| SCHEMBL22965154 | 0.79 | KDM4E (0.62) | PTGDR2FAAHKDM4EHSD17B10TNF | |
| SCHEMBL18250317 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAGPR55HTT | |
| SCHEMBL4175599 | 0.78 | KDM4E (0.66) | PTGDR2SMN1; SMN2KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364875-A | Anticholesterol agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993023392-A1 | IMIDAZOLES LINKED TO BICYCLIC HETEROCYCLIC GROUPS FOR THE TREATMENT OF ATHEROSCLEROSIS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |