Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743204 | 1.00 | MAOB (0.39) | MAOBHIF1AMEN1KMT2APLA2G1B | |
| SCHEMBL6839059 | 0.93 | PTGS2 (0.34) | HIF1AKMT2APLA2G1BATG4B | |
| SCHEMBL7467513 | 0.91 | MAOB (0.41) | MAOBHIF1AMEN1KMT2APLA2G1B | |
| SCHEMBL7467515 | 0.91 | MAOB (0.41) | MAOBHIF1AMEN1KMT2APLA2G1B | |
| SCHEMBL7736847 | 0.87 | MAOB (0.45) | MAOBHIF1ANR4A2 | |
| SCHEMBL6841529 | 0.87 | MAOB (0.45) | MAOBHIF1ANR4A2 | |
| SCHEMBL6841787 | 0.86 | PTGS2 (0.38) | HIF1A | |
| SCHEMBL8711326 | 0.86 | PTGS2 (0.38) | HIF1A | |
| SCHEMBL8541846 | 0.84 | MAOB (0.38) | MAOBMEN1KMT2APLA2G1BATG4B | |
| SCHEMBL7470221 | 0.84 | HIF1A (0.49) | MAOBHIF1ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |