Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841787 | 1.00 | PTGS2 (0.38) | PTGS2HIF1AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL6839059 | 0.93 | PTGS2 (0.34) | PTGS2HIF1ASMN1; SMN2NPC1 | |
| SCHEMBL828229 | 0.88 | HIF1A (0.47) | PTGS2HIF1AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL828228 | 0.88 | HIF1A (0.47) | PTGS2HIF1AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL7743204 | 0.86 | MAOB (0.39) | HIF1A | |
| SCHEMBL7743200 | 0.86 | MAOB (0.39) | HIF1A | |
| SCHEMBL8725188 | 0.84 | HIF1A (0.40) | PTGS2HIF1A | |
| SCHEMBL8725191 | 0.84 | HIF1A (0.40) | PTGS2HIF1A | |
| SCHEMBL7863544 | 0.84 | HIF1A (0.40) | PTGS2HIF1A | |
| SCHEMBL7736847 | 0.83 | MAOB (0.45) | HIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876333-A1 | PROCESS FOR THE PREPARATION OF PESTICIDES | Novartis AG (CH) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997020808-A1 | PROCESS FOR THE PREPARATION OF PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |