Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369117 | 0.97 | CES2 (0.48) | ALDH1A1SMN1; SMN2KMT2ACRHBPCRHR2 | |
| SCHEMBL8812280 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2ACRHBPCRHR2 | |
| SCHEMBL7377386 | 0.84 | MAPT (0.45) | ALDH1A1SMN1; SMN2KMT2APKMMAPT | |
| SCHEMBL18668281 | 0.83 | KMT2A (0.53) | ALDH1A1SMN1; SMN2KMT2APKMMAPT | |
| SCHEMBL7375065 | 0.81 | CRHBP (0.52) | ALDH1A1SMN1; SMN2KMT2ACRHBPCRHR2 | |
| SCHEMBL7374177 | 0.80 | CRHBP (0.44) | ALDH1A1SMN1; SMN2KMT2ACRHBPCRHR2 | |
| SCHEMBL7371730 | 0.80 | CRHBP (0.51) | ALDH1A1SMN1; SMN2CRHBPCRHR2MAPT | |
| SCHEMBL10373835 | 0.80 | ATM (0.54) | ALDH1A1SMN1; SMN2KMT2ACRHBPCRHR2 | |
| SCHEMBL7748629 | 0.79 | MAPT (0.45) | ALDH1A1SMN1; SMN2KMT2APKMMAPT | |
| SCHEMBL7370750 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |