Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668281 | 0.92 | KMT2A (0.53) | MAPTKMT2ASMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL7369117 | 0.82 | CES2 (0.48) | MAPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7743974 | 0.79 | ALDH1A1 (0.46) | MAPTKMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL29617334 | 0.77 | KMT2A (0.55) | MAPTKMT2ASMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL9705584 | 0.76 | HTT (0.41) | MAPTKMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL7372957 | 0.75 | ALDH1A1 (0.47) | NPSR1ALDH1A1 | |
| SCHEMBL7409011 | 0.74 | KMT2A (0.45) | MAPTKMT2ASMN1; SMN2MEN1USP2 | |
| SCHEMBL18249413 | 0.74 | KMT2A (0.46) | MAPTKMT2ASMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL7373632 | 0.74 | GPBAR1 (0.46) | POLBMAOA | |
| SCHEMBL18668268 | 0.74 | MAPT (0.52) | MAPTKMT2ASMN1; SMN2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |