Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 3/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817925 | 0.85 | KMT2A (0.45) | KMT2AALDH1A1LMNAHTTHPGD | |
| SCHEMBL8814617 | 0.80 | CHRNB2 (0.47) | ALDH1A1LMNAHTTCHRNB2CHRNB4 | |
| SCHEMBL7751057 | 0.78 | AVPR2 (0.51) | KMT2ALMNAMTTPPPARG | |
| SCHEMBL8614650 | 0.77 | KMT2A (0.58) | KMT2AALDH1A1LMNAHPGDCHRNB2 | |
| SCHEMBL7515855 | 0.77 | KMT2A (0.50) | KMT2AALDH1A1LMNAHPGDMTTP | |
| SCHEMBL7378365 | 0.75 | PPARD (0.45) | KMT2AALDH1A1LMNACHRNB2CHRNB4 | |
| SCHEMBL7378362 | 0.75 | PPARD (0.45) | KMT2AALDH1A1LMNACHRNB2CHRNB4 | |
| SCHEMBL8816842 | 0.74 | KMT2A (0.52) | KMT2AALDH1A1LMNAHPGDCHRNB2 | |
| SCHEMBL8816782 | 0.72 | CHRNB2 (0.54) | KMT2AALDH1A1LMNAHTTHPGD | |
| SCHEMBL8817468 | 0.72 | KMT2A (0.52) | KMT2AALDH1A1LMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |