Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814617 | 0.92 | CHRNB2 (0.47) | LMNAGAAHTTHDAC1MAPT | |
| SCHEMBL7743977 | 0.85 | KMT2A (0.44) | KMT2ALMNAHPGDHTTALDH1A1 | |
| SCHEMBL7751057 | 0.81 | AVPR2 (0.51) | KMT2ALMNAHDAC1MTTPPOLB | |
| SCHEMBL10401177 | 0.79 | GAA (0.54) | KMT2ALMNAGAAHTTMAPT | |
| SCHEMBL8614650 | 0.79 | KMT2A (0.58) | KMT2ALMNAHPGDHDAC1MAPT | |
| SCHEMBL7515855 | 0.78 | KMT2A (0.50) | KMT2ALMNAHPGDHDAC1MAPT | |
| SCHEMBL8816842 | 0.76 | KMT2A (0.52) | KMT2ALMNAHPGDHDAC1MAPT | |
| SCHEMBL7372350 | 0.75 | AVPR2 (0.43) | KMT2ALMNAGAAMAPTATM | |
| SCHEMBL8074321 | 0.74 | ALDH1A1 (0.54) | LMNAHPGDHTTMAPTTSHR | |
| SCHEMBL8816782 | 0.74 | CHRNB2 (0.54) | KMT2ALMNAHPGDHTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |