Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817468 | 0.81 | KMT2A (0.52) | KMT2AHDAC1KDM1AEGFRLMNA | |
| SCHEMBL8614650 | 0.79 | KMT2A (0.58) | KMT2AHDAC1TP53LMNAMAPT | |
| SCHEMBL8817925 | 0.78 | KMT2A (0.45) | KMT2AHDAC1KDM1APOLBLMNA | |
| SCHEMBL7743977 | 0.77 | KMT2A (0.44) | KMT2ALMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL7515848 | 0.76 | L3MBTL1 (0.42) | KMT2APOLBTP53MAPTKDM4E | |
| SCHEMBL7751057 | 0.75 | AVPR2 (0.51) | KMT2AHDAC1POLBLMNAMTTP | |
| SCHEMBL8816842 | 0.74 | KMT2A (0.52) | KMT2AHDAC1KDM1ATP53LMNA | |
| SCHEMBL4550597 | 0.74 | KMT2A (0.50) | KMT2ALMNAMAPTKDM4EHPGD | |
| SCHEMBL8510267 | 0.74 | RECQL (0.40) | KMT2APOLBTP53MAPTNPSR1 | |
| SCHEMBL8814617 | 0.73 | CHRNB2 (0.47) | HDAC1POLBLMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |