Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515855 | 0.81 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL8816306 | 0.77 | MAPT (0.48) | KMT2AKDM4EHDAC1HDAC6MAPT | |
| SCHEMBL7366911 | 0.76 | RAB9A (0.45) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL7743977 | 0.72 | KMT2A (0.44) | KMT2ASMN1; SMN2LMNAKDM4EL3MBTL1 | |
| SCHEMBL8814617 | 0.72 | CHRNB2 (0.47) | SMN1; SMN2LMNAKDM4EHDAC1MAPT | |
| SCHEMBL8817925 | 0.72 | KMT2A (0.45) | KMT2AMEN1LMNAKDM4EHDAC1 | |
| SCHEMBL8614650 | 0.72 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6256451 | 0.71 | CA1 (0.60) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL3960697 | 0.71 | RAB9A (0.64) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL1123418 | 0.70 | NR1H4 (0.65) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |