Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 10/20 | 0.35 |
| ▸ | TK2 | O00142 | 10/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706308 | 0.87 | RNASE1 (0.39) | TK1TK2HPGD | |
| SCHEMBL1705788 | 0.84 | ABCG2 (0.34) | TK1TK2 | |
| SCHEMBL6756344 | 0.82 | RNASE1 (0.37) | TK1TK2HPGD | |
| SCHEMBL7743997 | 0.80 | TK1 (0.37) | TK1TK2 | |
| SCHEMBL7908351 | 0.79 | TK2 (0.35) | TK1TK2 | |
| SCHEMBL9499952 | 0.78 | — | — | |
| SCHEMBL29414069 | 0.78 | LMNA (0.37) | — | |
| SCHEMBL3612842 | 0.78 | PYGM (0.38) | TK1TK2 | |
| SCHEMBL7640426 | 0.75 | RNASE1 (0.39) | TK1TK2 | |
| SCHEMBL29414053 | 0.75 | RNASE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8825411-B2 | Design, synthesis and assembly of synthetic nucleic acids | DNA TWOPOINTO, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| EP-2441769-B1 | Design, synthesis and assembly of synthetic nucleic acids | REPLIGEN CORP (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20130196864-A1 | DESIGN, SYNTHESIS AND ASSEMBLY OF SYNTHETIC NUCLEIC ACIDS | DNA TWOPOINTO, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| CN-101921744-B | Interfering target site sequence of P gene, small interfering RNA and composition and application thereof | SUZHOU RIBO LIFE SCIENCE CO LTD | 2012-09-05 | — | — | CN | disclosed |
| EP-2441769-A1 | Design, synthesis and assembly of synthetic nucleic acids | REPLIGEN CORPORATION (US) | 2012-04-18 | — | — | EP | disclosed |
| CN-101921745-B | Interfering target site sequence of MATP gene, small interfering nucleic acid, composition and application | SUZHOU RIBO LIFE SCIENCE CO LTD | 2012-04-18 | — | — | CN | disclosed |
| CN-102028947-A | Inhibitor, inhibitor composition and inhibiting method of FAM3B gene, fatty liver treatment method and pharmaceutical application of inhibitor | SUZHOU RIBO LIFE SCIENCE CO LTD | 2011-04-27 | — | — | CN | disclosed |
| CN-101921745-A | Interfering target site sequence of MATP (Membrane-associated Transport Protein) gene and small interfering RNA and application | SUZHOU RIBO LIFE SCIENCE CO LTD | 2010-12-22 | — | — | CN | disclosed |
| CN-101921744-A | Interfering target site sequence of P gene, small interfering RNA and composition and application thereof | SUZHOU RIBO LIFE SCIENCE CO LTD | 2010-12-22 | — | — | CN | disclosed |
| US-20090317873-A1 | Design, synthesis and assembly of synthetic nucleic acids | DNA TWOPOINTO, INC. | 2009-12-24 | — | — | US | disclosed |
| CN-1322898-C | Small interference RNA molecule SiRNA capable of attacking human hepatitis B virus and application thereof | HANGZHOU NEW RAYJAY BIOMED COR (CN) | 2007-06-27 | — | — | CN | disclosed |
| CN-1314698-C | Micromolecule interference RNA aiming at middle period factor gene and use thereof | UNIV ZHEJIANG (CN) | 2007-05-09 | — | — | CN | disclosed |
| EP-1771579-A2 | DESIGN, SYNTHESIS AND ASSEMBLY OF SYNTHETIC NUCLEIC ACIDS | DNA TWOPOINTO INC. (US) | 2007-04-11 | — | — | EP | disclosed |
| CN-1281279-C | Small interference ribonucleic acid molecule for epidermal growth facor gene and its use | UNIV ZHEJIANG (CN) | 2006-10-25 | — | — | CN | disclosed |
| WO-2005115102-A2 | DESIGN, SYNTHESIS AND ASSEMBLY OF SYNTHETIC NUCLEIC ACIDS | DNA TWOPOINTO, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| CN-1663957-A | Micromolecule interference RNA aiming at middle period factor gene and use thereof | UNIV ZHEJIANG (CN) | 2005-09-07 | — | — | CN | disclosed |
| CN-1651450-A | Small interference RNA molecule (SiRNA) capable of effectively killing and wounding tumour cell pointed at PLK1 mRNA, its mixture and use | HANGZHOU XINRUIJIA BIOMEDICINE (CN) | 2005-08-10 | — | — | CN | disclosed |
| CN-1616476-A | Small interference ribonucleic acid molecule for epidermal growth facor gene and its use | UNIV ZHEJIANG (CN) | 2005-05-18 | — | — | CN | disclosed |
| CN-1590545-A | Small interference RNA molecule (siRNA) of attacking SARS virus mRNA melecule and application | HANGZHOU XINRUIJIA BIOLOG MEDI (CN) | 2005-03-09 | — | — | CN | disclosed |
| CN-1566131-A | Small interference RNA molecule SiRNA capable of attacking human hepatitis B virus and application thereof | HANGZHOU NEW RAYJAY BIOMED COR (CN) | 2005-01-19 | — | — | CN | disclosed |