Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30028803 | 0.99 | ALDH1A1 (0.52) | ALDH1A1PKMNPSR1OPRK1KCNH2 | |
| SCHEMBL8912103 | 0.95 | L3MBTL1 (0.56) | ALDH1A1PKMNPSR1OPRK1L3MBTL1 | |
| SCHEMBL8914329 | 0.88 | ALDH1A1 (0.47) | ALDH1A1PKMNPSR1OPRK1L3MBTL1 | |
| SCHEMBL915985 | 0.88 | ALDH1A1 (0.50) | ALDH1A1PKMNPSR1L3MBTL1ATM | |
| SCHEMBL30029574 | 0.87 | OPRK1 (0.49) | ALDH1A1PKMNPSR1OPRK1L3MBTL1 | |
| SCHEMBL4524255 | 0.86 | SLC6A4 (0.57) | OPRK1KCNH2L3MBTL1KMT2AUSP2 | |
| SCHEMBL15934617 | 0.83 | OPRK1 (0.48) | ALDH1A1PKMNPSR1OPRK1KCNH2 | |
| SCHEMBL21159397 | 0.83 | OPRK1 (0.48) | ALDH1A1PKMNPSR1OPRK1KCNH2 | |
| SCHEMBL29638013 | 0.83 | OPRK1 (0.48) | ALDH1A1PKMNPSR1OPRK1KCNH2 | |
| SCHEMBL29641135 | 0.83 | OPRK1 (0.48) | ALDH1A1PKMNPSR1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221879-B1 | 8-azabicyclo[3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors | SANOFI-SYNTHELABO (FR) | 2001-04-24 | — | — | US | disclosed |