Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744542 | 0.95 | ALDH1A1 (0.53) | L3MBTL1KMT2AUSP2OPRK1ATM | |
| Hydrochloric Acid SCHEMBL30028803 | 0.94 | ALDH1A1 (0.52) | L3MBTL1KMT2AUSP2OPRK1ATM | |
| SCHEMBL30029574 | 0.92 | OPRK1 (0.49) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL915985 | 0.86 | ALDH1A1 (0.50) | L3MBTL1KMT2AATMALDH1A1PKM | |
| SCHEMBL8914329 | 0.86 | ALDH1A1 (0.47) | L3MBTL1KMT2AUSP2OPRK1ATM | |
| SCHEMBL4524255 | 0.81 | SLC6A4 (0.57) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL17595311 | 0.81 | KMT2A (0.50) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL30028945 | 0.81 | LMNA (0.62) | L3MBTL1KMT2AUSP2OPRK1LMNA | |
| SCHEMBL30029015 | 0.79 | ALDH1A1 (0.42) | L3MBTL1KMT2AUSP2OPRK1ATM | |
| SCHEMBL15934617 | 0.79 | OPRK1 (0.48) | OPRK1ALDH1A1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175402-A1 | QUINUCLIDINE-3-ONE DERIVATIVES | APREA THERAPEUTICS AB (SE) | 2022-08-25 | — | — | WO | disclosed |
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| US-5422354-A | Quinuclidine derivatives | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0540526-A1 | QUINUCLIDINE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001688-A1 | QUINUCLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-02-06 | — | — | WO | disclosed |