Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.36 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.36 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744126 | 0.78 | CCKBR (0.42) | CCKBRBDKRB1KCNH2 | |
| SCHEMBL7743998 | 0.73 | KCNH2 (0.61) | CCKBRBDKRB1KCNH2 | |
| SCHEMBL7738908 | 0.73 | KCNH2 (0.45) | CCKBRKCNH2NOTCH1NOTCH3RBPJ | |
| SCHEMBL7744128 | 0.69 | KCNH2 (0.52) | CCKBRKCNH2 | |
| SCHEMBL7744120 | 0.68 | KCNH2 (0.36) | CCKBRBDKRB1KCNH2 | |
| SCHEMBL7743995 | 0.68 | KCNH2 (0.36) | CCKBRBDKRB1KCNH2 | |
| SCHEMBL8620108 | 0.67 | KCNH2 (0.77) | CCKBRKCNH2 | |
| SCHEMBL7744124 | 0.67 | KCNH2 (0.55) | CCKBRKCNH2 | |
| SCHEMBL7744000 | 0.67 | KCNH2 (0.55) | CCKBRKCNH2 | |
| SCHEMBL9214723 | 0.67 | BDKRB1 (0.49) | CCKBRBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010216-A1 | ANTIARRHYTHMIC COMPOUNDS | MERCK & CO., INC. (US) | 2001-02-15 | — | — | WO | disclosed |