Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 4/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 6/20 | 0.32 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.32 |
| ▸ | MICA | Q29983 | 1/20 | 0.32 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 2/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744120 | 1.00 | KCNH2 (0.36) | KCNH2XIAPGALR3CCKBRKLRK1 | |
| SCHEMBL7744591 | 0.87 | KCNH2 (0.45) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL7744132 | 0.87 | KCNH2 (0.45) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL7744126 | 0.86 | CCKBR (0.42) | KCNH2CCKBRKLRK1MICARAET1L | |
| SCHEMBL7744000 | 0.78 | KCNH2 (0.55) | KCNH2XIAPCCKBRCCKARPSEN1 | |
| SCHEMBL7744124 | 0.78 | KCNH2 (0.55) | KCNH2XIAPCCKBRCCKARPSEN1 | |
| SCHEMBL7744698 | 0.70 | KCNH2 (0.47) | KCNH2XIAPGALR3SCN9A | |
| SCHEMBL7744588 | 0.68 | CCKBR (0.44) | KCNH2CCKBRBDKRB1 | |
| SCHEMBL7744135 | 0.67 | KCNH2 (0.72) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL7744593 | 0.67 | KCNH2 (0.72) | KCNH2CCKBRCCKARPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010216-A1 | ANTIARRHYTHMIC COMPOUNDS | MERCK & CO., INC. (US) | 2001-02-15 | — | — | WO | disclosed |