Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744822 | 1.00 | IDE (0.39) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7745349 | 0.89 | CCR5 (0.40) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7745343 | 0.89 | CCR5 (0.40) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7744802 | 0.82 | CCR5 (0.47) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7744770 | 0.81 | ALDH1A1 (0.42) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7744775 | 0.81 | ALDH1A1 (0.42) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7740114 | 0.80 | IDE (0.45) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7745215 | 0.79 | IDE (0.38) | IDEKMT2AALDH1A1CCR5GAA | |
| SCHEMBL7744835 | 0.78 | IDE (0.46) | IDEKMT2APRNPPOLBRXFP1 | |
| SCHEMBL7745262 | 0.78 | CCR5 (0.43) | IDEKMT2APRNPPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | claimed |
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |