SCHEMBL7744865

SCHEMBL7744865

C#CCOc1ccccc1Oc1c[c]c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAOB P27338 5/20 0.37
MAPT P10636 2/20 0.35
PGK1 P00558 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
SLC6A4 P31645 1/20 0.33
IDO1 P14902 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DRD2 P14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1531130 0.86 LMNA (0.42) LMNAMAOBPGK1SLC6A2SLC6A3
SCHEMBL7745226 0.83 GSTP1 (0.39) LMNAMAOBPGK1MAOA
SCHEMBL7740123 0.82 MAOB (0.38) LMNAMAOBPGK1KMT2AMAOA
SCHEMBL7740056 0.77 L3MBTL1 (0.42) MAPTSLC6A2SLC6A3HPGDSLC6A4
SCHEMBL7744203 0.75 STK39 (0.41) LMNAMAPTSLC6A2SLC6A3HPGD
SCHEMBL16394998 0.74 MAOB (0.33) LMNAMAOBMAPTPGK1HPGD
SCHEMBL7740071 0.73 USP2 (0.44) LMNAMAPTHPGDTSHRNPC1
SCHEMBL7931478 0.71 POLB (0.36) LMNAMAOBHPGDTSHRKMT2A
SCHEMBL5981851 0.71 MAPT (0.50) LMNAMAOBMAPTHPGDTSHR
SCHEMBL30663731 0.71 MAPT (0.56) MAOBMAPTHPGDTSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009087-A1 SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-08 WO disclosed