SCHEMBL7744203

SCHEMBL7744203

Oc1ccccc1Oc1c[c]c(F)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK39 Q9UEW8 1/20 0.41
TTR P02766 5/20 0.40
SLC6A2 P23975 3/20 0.40
SLC6A3 Q01959 3/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
NR1I2 O75469 1/20 0.40
PGR P06401 1/20 0.40
HSP90AA1 P07900 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
HSPA5 P11021 1/20 0.40
HPGD P15428 1/20 0.40
CBR1 P16152 1/20 0.40
TBXA2R P21731 1/20 0.40
AGTR1 P30556 1/20 0.40
GAA P10253 2/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740056 0.81 L3MBTL1 (0.42) TTRSLC6A2SLC6A3MAPTHPGD
SCHEMBL7740190 0.76 MEN1 (0.41) STK39HSP90AA1KMT2A
SCHEMBL7740258 0.76 STK39 (0.44) STK39HSP90AA1TSHR
SCHEMBL7744865 0.75 LMNA (0.39) SLC6A2SLC6A3LMNAMAPTHPGD
SCHEMBL1123331 0.74 TTR (0.48) STK39TTRSLC6A2SLC6A3LMNA
SCHEMBL7740071 0.72 USP2 (0.44) LMNAMAPTHPGDGAATSHR
SCHEMBL6246195 0.72 SLC6A2 (0.40) STK39TTRSLC6A2SLC6A3LMNA
SCHEMBL1532088 0.72 ALDH1A1 (0.54) STK39TTRSLC6A2SLC6A3LMNA
SCHEMBL240470 0.71 TTR (0.76) STK39TTRSLC6A2SLC6A3LMNA
SCHEMBL7614067 0.71 ALDH1A1 (0.41) LMNAMAPTHPGDGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009087-A1 SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-08 WO disclosed