Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028236 | 1.00 | ACE (0.47) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL8595093 | 0.94 | ACE (0.51) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL9067648 | 0.88 | ACE (0.46) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL10720961 | 0.87 | KMT2A (0.38) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL9067650 | 0.85 | ACE (0.40) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL9067249 | 0.80 | GPR139 (0.47) | ACEMMEKMT2AMEN1GPR139 | |
| SCHEMBL8980460 | 0.76 | KMT2A (0.46) | ACEKMT2AMAPTMEN1HPGD | |
| SCHEMBL8904451 | 0.76 | MAPK1 (0.39) | ACEMMEALDH1A1KMT2AMAPT | |
| SCHEMBL7293621 | 0.75 | KDM4E (0.59) | KMT2AMAPTMEN1KDM4EGPR139 | |
| SCHEMBL7515133 | 0.75 | KDM4E (0.59) | KMT2AMAPTMEN1KDM4EGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7041433-A | — | — | None | — | — | JP | disclosed |
| EP-0831938-A4 | RADIOLABELED PEPTIDE COMPOSITIONS FOR SITE-SPECIFIC TARGETING | MALLINCKRODT MEDICAL INC (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0692982-B1 | RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS | DU PONT PHARM CO (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0995761-A2 | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders | Dupont Pharmaceuticals Company (US) | 2000-04-26 | — | — | EP | disclosed |
| US-6022523-A | NOVEL CYCLIC COMPOUNDS CONTAINING CARBOCYCLIC AND HETEROCYCLIC RING SYSTEMS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0910416-A2 | RADIOPHARMACEUTICAL COMPOSITIONS CAPABLE OF LOCALIZING AT SITES OF THROMBUS | G.D. SEARLE & CO. (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5879657-A | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| WO-1997047329-A9 | RADIOPHARMACEUTICAL COMPOSITIONS CAPABLE OF LOCALIZING AT SITES OF THROMBUS | — | 1998-07-02 | — | — | WO | disclosed |
| EP-0831938-A1 | RADIOLABELED PEPTIDE COMPOSITIONS FOR SITE-SPECIFIC TARGETING | MALLINCKRODT MEDICAL, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997047329-A2 | RADIOPHARMACEUTICAL COMPOSITIONS CAPABLE OF LOCALIZING AT SITES OF THROMBUS | G.D. SEARLE & CO. (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1994022494-A1 | RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0614379-A1 | TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING | Diatide, Inc. (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0284071-B1 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORP (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5245018-A | Reaction of pertechnetate and a mercaptoacetyltripeptide, kidney diagnosis | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| WO-1993010747-A2 | TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING | DIATECH, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0483704-A1 | Process for preparing a radiopharmaceutical composition | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5091514-A | Antitumor, anticarcinogenic agents | NEORX CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-4965392-A | DIAGNOSIS, RADIOTHERAPY OF TUMORS | NEORX CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0284071-A2 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORPORATION (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0247866-A1 | Coupling agents for radiolabeling proteins | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1987-12-02 | — | — | EP | disclosed |