Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | MME | P08473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745199 | 0.88 | ACE (0.47) | ACEMMEALDH1A1MAPTLMNA | |
| SCHEMBL2028236 | 0.88 | ACE (0.47) | ACEMMEALDH1A1MAPTLMNA | |
| SCHEMBL8595093 | 0.82 | ACE (0.51) | ACEMMEALDH1A1MAPTLMNA | |
| SCHEMBL9067249 | 0.81 | GPR139 (0.47) | ACEMMEGPR139KMT2AMEN1 | |
| SCHEMBL9068127 | 0.78 | NOD2 (0.43) | ALDH1A1LMNAGPR139OPRD1OPRM1 | |
| SCHEMBL9067650 | 0.78 | ACE (0.40) | ACEMMEALDH1A1MAPTGPR139 | |
| SCHEMBL28231704 | 0.77 | SMN1; SMN2 (0.54) | ACEMMEALDH1A1MAPTLMNA | |
| SCHEMBL28231702 | 0.77 | SMN1; SMN2 (0.54) | ACEMMEALDH1A1MAPTLMNA | |
| SCHEMBL9067652 | 0.77 | GPR139 (0.57) | ACEMMEALDH1A1MAPTGPR139 | |
| SCHEMBL9053361 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATDP1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534497-A | RADIOPHARMACEUTICALS; MEDICAL DIAGNOSIS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5187264-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT MEDICAL, INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0250013-B1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4849511-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0250013-A1 | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1987-12-23 | — | — | EP | disclosed |