Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744970 | 0.89 | CTNNB1 (0.47) | AGTR1AGTR2MEN1KMT2ACTNNB1 | |
| SCHEMBL7745482 | 0.75 | LMNA (0.47) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL7740405 | 0.74 | KDM4E (0.43) | MEN1KMT2ALMNAPOLBGAA | |
| SCHEMBL7745467 | 0.74 | TOP2A (0.49) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7745460 | 0.74 | TSHR (0.61) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7745216 | 0.73 | TSHR (0.50) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7745475 | 0.72 | AKR1B1 (0.41) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7745019 | 0.72 | KDM4E (0.47) | KMT2ALMNAALDH1A1POLBHPGD | |
| SCHEMBL8365513 | 0.72 | TP53 (0.45) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL7747798 | 0.72 | MEN1 (0.41) | MEN1KMT2ALMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |